This image and page layout were for an assignment about depression and PTSD (Post Traumatic Stress Disorder) and the project came out... very blue! 
 
I did the lineart first on watercolor paper, took off my glasses, applied water to the paper and then watercolor pigment to the water where I thought it best suited the piece. I've found that for loose coloring like this, it's best to remove my glasses so I don't get too invested into the details. Some of the red I splattered onto the page, but most of it I lightly placed onto the still-wet blue.
Above is the lineart, below is a portion of the colored piece scanned, totally unedited. (I did several scannings and compiled them in photoshop.)
Feeling Blue
Published:

Feeling Blue

A full-page spread for a mock article entitled Feeling Blue- the Truth about PTSD and Depression

Published: